IMAMURA Yasutada

School of Advanced Engineering Department of Chemistry and Life ScienceProfessor

Career

  • Apr. 2015 - Present
    Kogakuin University, School of Advanced Engineering Department of Chemistry and Life Science, Professor, Ph. D.
  • 2008 - Mar. 2015
    Kogakuin University, Faculty of Engineering, Department of Applied Chemistry
  • Apr. 2007 - Mar. 2008
    Associate Professor at Department of Applied Chemistry, Faculty of Engineering, Kogakuin University, Faculty of Engineering, Department of Applied Chemistry
  • Apr. 2006 - Mar. 2007
    Associate Professor at Department of Applied Chemistry, Faculty of Engineering, Kogakuin University, Faculty of Engineering, Department of Applied Chemistry
  • Apr. 2005 - Mar. 2006
    Part-time Lecturer / Biochemistry ( for Evening Program at Department of Chemical Design and Application) at Department of Applied Chemistry, Kogakuin University
  • Apr. 1994 - Mar. 2006
    Assistant Professor at Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Graduate School of Arts and Sciences
  • Sep. 1997 - Aug. 1999
    Visiting Scientist at Univesity of Wisconsin-Madison
  • Apr. 1990 - Mar. 1995
    Part-time Lecturer / Chemistry at School for Dental Hygienists, Faculty of Dentistry, Tokyo Medical and Dental University, Faculty of Dentistry
  • Nov. 1987 - Mar. 1994
    Assistant Professor at Department of Chemistry, College of Arts and Sciences, The University of Tokyo, College of Arts and Sciences

Educational Background

  • Apr. 1985 - Nov. 1987
    The University of Tokyo, graduate school of science
  • Apr. 1983 - Mar. 1985
    The University of Tokyo, Graduate school of science
  • Apr. 1978 - Mar. 1983
    The University of Tokyo, College of Arts and Sciences, Department of Pure and Applied Science

Degree

  • Mar. 1983
    教養学士, The University of Tokyo
  • Mar. 1985
    理学修士, The University of Tokyo
  • Sep. 1989
    理学博士, The University of Tokyo

Affiliated academic society

  • Apr. 2001 - Present
    The Japanese society for connective tissue research
  • 日本結合組織学会
  • マトリックス研究会
  • 日本生化学会
  • 高分子学会
  • International Society of Matrix Biology
  • Japan Matrix Club
  • The Japanese Biochemical Society
  • The society of Polymer Science, Japan
  • International Society of Matrix Biology

IDs

Research Field

  • Life sciences, Structural biochemistry, Structural Biochemistry
  • Life sciences, Cell biology, extracellular matrix
  • Life sciences, Biomaterials
  • Life sciences, Biomedical engineering

Research Keyword

  • Planaria
  • sea cucumber
  • Fibrillin
  • Elastin
  • Elastic fiber
  • angiogenesis
  • Fascia
  • collagen fiber
  • basement membrane
  • collagen
  • extracellular matrix

Research theme

  • 01 Apr. 2016 - Present
    Generation of non-triple helical collagen polypeptide chains and tumors
  • 2000 - Present
    Basement membrane structure created with type IV collagen aggregates that regulates cellular functions
    Basement membrane,type IV collagen,cellular function
  • 01 Apr. 2012 - Present
    Regulation of Cellular Functions by Type VI Collagen Aggregates
    Type VI Collagen Aggregates
  • 01 Apr. 2012 - Present
    Development of cell culture method using sea cucumber collagen fibers
  • 01 Apr. 2015 - Present
    Research on tissue regeneration through regulation of collagen biosynthesis via metabolic control
  • 01 Apr. 2018 - Present
    Elucidation of the collagen fiber structure in skin fascia

Books and other publications

  • 細胞外マトリックス実験法,ーコラーゲンの基礎研究から再生医療への応用まで
    Contributor
    25 Dec. 2021
    9784621306857
  • 組織工学ライブラリー3 マイクロロボティクスとバイオの融合 細胞社会学 大和雅之編
    Single work
    16 Sep. 2016
    9784339072631
  • 予防医学事典
    Joint work
    25 May 2005
  • 新訂版・表面科学の基礎と応用(日本表面科学会編)
    Joint work
    22 Jun. 2004
  • 新訂版・表面科学の基礎と応用(日本表面科学会編)
    Joint work
    Jun. 2004
  • 分子生物学・免疫学キーワード辞典第二版
    Joint work
    15 May 2003
  • 「細胞外マトリックス研究法[1]〜基礎知識からデータの解釈まで第I部. 生化学的研究法」
    Joint work
    20 May 1998
  • マトリックス 「 細胞機能と代謝マップ II. 細胞の動的機能」(日本生化学会編)
    Joint work
    1998
  • コラーゲンファミリー 「細胞接着 BioScience用語ライブラリー」宮坂昌之、矢原一郎編
    Joint work
    1996
  • 「例題で学ぶ代謝と生合成」(Schaum’s Outline Series)P.W.クーヘル/G.B.ラルストン著
    Joint translation
    15 Mar. 1993
  • 「例題で学ぶ生体構成物質」(Schaum’s Outline Series)P.W.クーヘル/G.B.ラルストン著
    Joint translation
    24 Sep. 1992
  • 「生命の第二の秘密」マックス・ペルツ著
    Joint translation
    12 Jun. 1991

Paper

MISC

Lectures, oral presentations, etc.

  • 浅層Fascia のコラーゲン線維構造
    25 Jun. 2023
  • NTH a1(IV)によるVE-カドヘリンのエンドサイトーシス:Endo180の関与
    25 Jun. 2023
  • 3 本らせん構造を持たない IV 型コラーゲンポリペプチド鎖 (NTH α1(IV)) は,VE- カドヘリンによる血管内皮細胞間の結合を抑制する
    26 Jun. 2022
  • Fascia の線維構造の解析
    25 Jun. 2022
  • トリfasciaの線維構造の解析
    20 Sep. 2020
  • 新規血管新生モデルによる基底膜形成メカニズムの解明
    14 Sep. 2020
  • 3次元電子顕微鏡を用いたコラーゲン細線維を束ねるグリコサミノグリカン鎖の立体構造解析
    14 Sep. 2020
  • Involvement of NTH α(IV) in formation of basement membrane-like structures around the endothelial cell network in a novel in vitro angiogenesis model
    Yongchol Shin; Akane Moriya; Yuta Tohnishi; Takafumi Watanabe; Yasutada Imamura
    18th international symposium on advanced technology, 13 Dec. 2019, International symposium on advanced technology
  • Collagen and NTH (non-triple helical collagen polypeptide)
    Yasutada Imamura
    18th international symposium on advanced technology, 13 Dec. 2019, International symposium on advanced technology
  • Enhancement of the tumor cell migration on fibronectin by the metalloproteinase from Ovophis okinavensis snake venom
    Yuna Saito; Yongchol Shin; and Yasutada Imamura
    18th international symposium on advanced technology, 13 Dec. 2019, International symposium on advanced technology
  • Inhibitory activity of sekothrixide on a drug efflux via P-glycoprotein
    Ryoki Haruyama; Yongchol Shin; and Yasutada Imamura
    18th international symposium on advanced technology, 13 Dec. 2019, International symposium on advanced technology
  • Elucidation of the mechanism of tumor cell migration through fibronectin using the metalloproteinase from Ovophis okinavensis’s crude venom
    03 Dec. 2019
  • 血管新生におけるアスコルビン酸の影響3 本らせん構造をとらないIV型コラーゲンポリペプチド鎖 (NTHα1(IV))産生
    31 May 2019
  • 疑似低酸素条件での 3 本らせん構造をもたない IV 型 コラーゲンポリペプチド鎖(NTHα1(IV))の産生
    31 May 2019
  • トリfasciaの線維構造研究法の確立
    31 May 2019
  • 真皮のコラーゲン細線維を束ねる糖鎖の立体構造
    31 May 2019
  • 気相条件における気生微細藻類Coelastrella sp. KGU-Y002のキサントフィルのエステル化
    05 Mar. 2019
  • 気生微細藻類Coccomyxa sp. KGU-D001の壁面培養の確立に向けた気相条件の検討
    05 Mar. 2019
  • 気生微細藻類が産生する抗菌活性を有する新規クロロフィル類の単離
    14 Nov. 2018
  • 気生微細藻類由来の抗菌活性を有する新規クロロフィル類の単離と構造推定
    25 Oct. 2018
  • 気生微細藻類と窒素固定菌による栄養源の相互供給が可能な共培養系の開発
    25 Oct. 2018
  • 気生微細藻類と窒素固定菌の共生系を利用した壁面培養法
    07 Sep. 2018
  • 気相培養における気生微細藻類 Coccomyxa sp. KGU-D001 の脂質蓄積と細胞内 CN 比
    06 Sep. 2018
  • 気生微細藻類由来の抗菌活性を有する新規クロロフィル類の単離とその産生株の探索
    06 Sep. 2018
  • 気相培養による気生微細藻類 Coelastrella sp. KGU-Y002 のカロテノイドのエステル化
    05 Sep. 2018
  • Plasminによる血漿および血栓中のvon Willebrand factor multimersの切断:止血及び線溶への影響
    30 Jun. 2018
  • ELISAを用いた尿中3-Hydroxyproline含有ペプチド測定法の開発と大腸癌マーカーとしての有用性の検討ELISAを用いた尿中3-Hydroxyproline含有ペプチド測定法の開発と大腸癌マーカーとしての有用性の検討
    29 Jun. 2018
  • 血管内皮細胞と線維芽細胞による共培養系スフェロイドを用いた血管新生系モデルにおける基底膜構築
    07 Dec. 2017
  • Extracellular matrix in planarians
    Kazuto Nakano; Yongchol Shin; Yasutada Imamura
    The 16th International Symposium on Advanced Technology, 02 Nov. 2017
  • Production of non-triple helical structure type Ⅳ collagen polypeptide (NTHα1(Ⅳ))
    17 Jun. 2017
  • 血管内皮細胞と線維芽細胞による共培養スフェロイドを用いた血管新生モデルにおけるⅣ型コラーゲンの局在
    17 Jun. 2017
  • ウシ角膜由来Ⅵ型コラーゲン会合体コート上での細胞培養
    17 Jun. 2017
  • 3 次元再構築による腱のプロテオグリカングリコサミノグリカン鎖のリングメッシュ構造について
    17 Jun. 2017
  • コラーゲンの歴史:コラーゲン概説
    26 Feb. 2017
  • ヒメハブ粗毒由来metalloproteinase MP09によるFibronectinの切断部位の特定と細胞遊走の促進
    30 Nov. 2016
  • 血管内皮細胞と線維芽細胞による共培養スフェロイドを用いた新規血管新生モデル
    30 Nov. 2016
  • Fibrin clotに取込まれたvon Willebrand factor multimersはPlaminによるfibrinの切断を促進する
    27 Sep. 2016
  • 血漿または fibrin clot での plasmin によるvon Willebrand factor multimer の切断
    04 Sep. 2016
  • Fibronectinへの細胞接着を特異的に阻害するヒメハブ粗毒由来P-III metalloproteinase MP09 の機能解析と阻害メカニズムの解明
    16 Jul. 2016
  • ウシ角膜由来Ⅵ型コラーゲン会合体を用いた細胞培養法
    24 Jun. 2016
  • 血漿中またはFibrin clot中でのPmによるVWFMの切断
    18 Jun. 2016
  • フィブロネクチンへの細胞接着を特異的に阻害するヒメハブ粗毒由来P-3 Metalloproteinase (MP09) の精製と 阻害メカニズムの解明
    03 Dec. 2015
  • 血漿中のplasminによるADAMTS13の切断とそのVWF切断活性の低下
    03 Dec. 2015
  • ヒト血漿中でのPlasminによる構造変化したVWFマルチマーの切断
    01 Dec. 2015
  • Incorporation of a peptide nucleic acid into a normal human fibroblast cell reduced type I collagen production
    Yasutada Imamura; Suzuka Tsuboi; Toru Sugiyama; Atsushi Kittaka; Yonchol Shin
    9th International Conference on Proteoglycans and 10th Pan Pacific Connective Tissue Societies Symposium, 25 Aug. 2015, 9th International Conference on Proteoglycans and 10th Pan Pacific Connective Tissue Societies Symposium
  • Isolation of a venom protein derived from the Ovophis okinavensis (Himehabu) which specifically inhibits cell adhesion to fibronectin and elucidation of the inhibition mechanism
    Hirotaka Yoshie; Yongchol Shin; Yuriko Okano; Toshihiro Takahashi; Takeshi Tohyama; Yasutada Imamura
    9th International Conference on Proteoglycans and 10th Pan Pacific Connective Tissue Societies Symposium, 25 Aug. 2015, 9th International Conference on Proteoglycans and 10th Pan Pacific Connective Tissue Societies Symposium
  • Plasminが及ぼすヒト血漿中のADAMTS13活性への影響
    22 May 2015
  • ナマココラーゲン線維間相互作用
    15 May 2015
  • 3本らせん構造を持たないIV型コラーゲンポリペプチド鎖の産生:培養条件と細胞局在の検討
    15 May 2015
  • フィブロネクチンへの細胞接着を特異的に阻害するヒメハブ粗毒由来タンパク質の同定と阻害メカニズムの解明 〜ヘビ毒を用いた細胞シート様構造体の作成〜
    15 May 2015
  • 3重らせん構造をとらない1本鎖IV型コラーゲンの血管基底膜特異的存在
    15 May 2015
  • デアザグアニン誘導体を持つ PNA モノマーの合成
    27 Mar. 2015
  • Factors on the sea cucumber collagen fibrils which affect interactions between fibrils
    Jun Igarashi; Shun Ito; Kazuya Noda; Yongchol Shin; Koji Muakami; Chihiro Mochizuki; Mitsunobu Sato; Yasutada Imamura
    The 1st Innovation Forum of Advanced Engineering Education, 02 Nov. 2014, SPACC21
  • Elucidation of the mechanism of ADAMTS13 cleavage by plasmin in blood plasma
    Haruki Miyake; Yongchol Shin; Yoshinobu Umetsu; Ryuichi Hiratsuka; Akifumi Takahashi; Kana Endo; Kenji Soejima; Yasutada Imamura
    The 1st Innovation Forum of Advanced Engineering Education, 02 Nov. 2014, Innovation Forum of Advanced Engineering Education
  • Isolation and characterization of venom protein derived from the Ovophis okinavensis (Himehabu) which specifically inhibit cell adhesion to fibronectin
    Hirotaka Yoshie; Yongchol Shin; Tishihiro Takahashi; Masaki Mizumi; Takeshi Touyama; Yasutada Imamura
    he 1st Innovation Forum of Advanced Engineering Education, 02 Nov. 2014, Innovation Forum of Advanced Engineering Education
  • Modified Deazaguanines for the Syntheis of PNA
    Toru Sugiyama; Keiko Kuwata; Yasutada Imamura; Yosuke Demizu; Masaaki Kurihara; Masashi Takano; Atsushi Kittaka
    第51回ペプチド討論会, 22 Oct. 2014
  • 血漿ADAMTS13のplasminによる切断の分子機構の解明
    18 Oct. 2014
  • フィブロネクチンへの細胞接着を特異的に阻害するヒメハブ粗毒由来タンパク質の単離と解析
    18 Oct. 2014
  • MC3T3-E1 細胞によるアパタイト沈着はナマココラーゲン線維により促進される
    06 Jun. 2014
  • Ⅳ型コラーゲンの3本らせん形成に及ぼす細胞培養条件の影響
    06 Jun. 2014
  • 血漿中でのplasminによるADAMTS13の切断にクリングルドメインが関与する
    31 May 2014
  • 細胞外基質への細胞接着を特異的に阻害するヒメハブ粗毒由来タンパク質の探索
    03 Dec. 2013
  • TYPE I COLLAGEN PRODUCED BY CELLS IN ASCORBATE DEPLETION SHOWS A LOWER DENATURATION TEMPERATURE
    Mineo; T.; Shin; Y.; Kitada; K.; Hara; S.; Uchida; T. Imamura; Y.
    9th Pan Pacific Connective Tissue Societies Symposium, 26 Nov. 2013, Pan Pacific Connective Tissue Societies
  • Sea Cucumber Collagen Fibrils As Cell Culture Substrates
    Imamura; Y.; Shinbo; T.; Amano; A.; Kodama; M.; Iseki; Y.; Miyazaki; H.; Shin; Y.
    9th Pan Pacific Connective Tissue Societies Symposium, 26 Nov. 2013, Pan Pacific Connective Tissue Societies
  • 表面粗さが異なるアノード酸化ポーラスアルミナ皮膜上での細胞培養
    23 Sep. 2013
  • ヒト血漿へのストレプトキナーゼ添加によって活性化したplasminは,血漿中のADAMTS13を切断する
    09 Jun. 2013
  • 孔径および表面粗さを制御したアノード酸化ポーラスアルミナ皮膜上での細胞培養
    07 Jun. 2013
  • β-Lys PNAの合成
    28 Mar. 2013
  • TYPE I COLLAGEN PRODUCED BY CELLS IN ASCORBATE DEPLETION SHOWS A LOWER DENATURATION TEMPERATURE
    2013
  • Sea Cucumber Collagen Fibrils As Cell Culture Substrates
    2013
  • Plasmin activated by streptokinase derived from hemolytic streptococcus cleaves ADAMTS13 in human plasma
    16 Dec. 2012
  • リジン側鎖を持ったβキラルぺプチド核酸の合成
    07 Nov. 2012
  • 構造制御したアノード酸化ポーラスアルミナ皮膜上における細胞増殖
    01 Nov. 2012
  • Development of blood vessel substitutes for chemical library screening
    Yongchol Shin; Yu Matsushita; Yui Sakakibara; Takahisa Shinbo; Kazuaki Yanagawa; Yasutada Imamura
    The 11th International Symposium on Advanced Technology, 30 Oct. 2012
  • CAPILLARY-LIKE STRUCTURE FORMED BY VASCULAR ENDOTHELIAL CELLS ON SEA CUCUMBER COLLAGEN FIBRILS
    Takahisa Shinbo; Yongchol Shin; Yasutada Imamura
    The 11th International Symposium on Advanced Technology, 30 Oct. 2012
  • Concerted and graded arrangement of collagen fibrils in the equine superficial digital flexor tendon
    Takafumi Watanabe; Yasutada Imamura; Daisuke Suzuki; Kazushige Takehana4 and Kohzy Hiramatsu
    XXIIIrd Meeting of the Federation of the European Connective Tissue Societies, 27 Aug. 2012, Federation of the European Connective Tissue Societies
  • 細胞増殖性に対するアノード酸化ポーラスアルミナ皮膜の微細構造の影響
    08 Aug. 2012
  • ナマコ由来コラーゲン線維を用いた血管内皮細胞の管腔形成
    06 Jun. 2012
  • 細胞増殖性に及ぼすアノード酸化ポーラスアルミナ皮膜の構造の影響
    Jun. 2012
  • Characterization of the snake venom protein from the crude venom of Naja atra(Taiwan cobra) that inhibits binding of the tumor cell to type IV collagen
    26 Mar. 2012
  • The artificial blood vessel that mimics in vivo environment-Morphology and function of vascular endothelical cells cultured in long-term on the aggregates of type IV collagen-
    26 Mar. 2012
  • IV型コラーゲンを取り入れた生体内環境を模した人工血管の可能性
    10 Mar. 2012
  • Ⅳ型コラーゲンを取り入れた生体内環境を模した人工血管の可能性―IV型コラーゲン会合体上で長期培養した血管内皮細胞の形態、機能の検討―
    2012
  • Concerted and graded arrangement of collagen fibrils in the equine superficial digital flexor tendon
    2012
  • Development of blood vessel substitutes for chemical library screening
    2012
  • CAPILLARY-LIKE STRUCTURE FORMED BY VASCULAR ENDOTHELIAL CELLS ON SEA CUCUMBER COLLAGEN FIBRILS
    2012
  • Characterization of the snake venom protein from the crude venom of <i>Naja atra<i>(Taiwan cobra) that inhibits binding of the tumor cell to type IV collagen
    2012
  • Plasmin activated by streptokinase derived from hemolytic streptococcus cleaves ADAMTS13 in human plasma
    2012
  • Cell Activation Characteristics on Structurally Controlled Surfaces of Aluminum
    S. Ono; Y. Kuroda; H. Asoh and Y. Imamura
    62nd Annual Meeting of the International Society of Electrochemistry, 11 Sep. 2011, the International Society of Electrochemistry
  • 表面微細構造による金属材料の生体適合性制御
    04 Jun. 2011
  • Single-chain type IV collagen (SCCOL-IV), an alternative gene product of COL4A1 as a therapeutic target in tumor tissue expansion as well as a diagnostic marker.
    Kazuhiro Tokunaka; Arihiro Tomura; Takamichi Sato; Kan Saiga; Chieko Seno; Hidemitsu Sugihara; Yasutada Imamura; Toshihiko Hayashi; Makoto Morita
    American Association for Cancer Research Annual Meeting 2011, 03 Apr. 2011, American Association for Cancer Research
  • 4位置換キラルPNAの合成
    28 Mar. 2011
  • 細胞の初期接着性に及ぼすアノード酸化皮膜の孔形態の影響
    17 Mar. 2011
  • Single-chain type IV collagen (SCCOL-IV), an alternative gene product of COL4A1 as a therapeutic target in tumor tissue expansion as well as a diagnostic marker.
    2011
  • Cell Activation Characteristics on Structurally Controlled Surfaces of Aluminum
    2011
  • Synthesis of 4-Substituted Chiral PNA Monomers
    Toru Sugiyama; Yasutada Imamura; Masaaki Kurihara; Masashi Takano4 and Atsushi Kittaka
    5th International Peptide Symposium in conjunction with 47th Japanese Peptide Symposium, 04 Dec. 2010, Japanese Peptide Society
  • 細胞形態および接着性に対するアノード酸化ポーラス皮膜の孔径の影響
    18 Nov. 2010
  • 細胞増殖に及ぼすアノード酸化ポーラス皮膜の孔形状の影響
    04 Nov. 2010
  • Cell clump formation induced by sea cucumber collagen fibrils
    Masashige Kodama; Yohsuke Iseki; Yongchol Shin; Yasutada Imamura
    The Joint Meeting of the 42nd Annual Meeting of Japanese Society for Connective Tissue Research & the 57th Annual Meeting of Japan Matrix Club, 19 Aug. 2010
  • ナマココラーゲン線維による細胞凝集体の形成
    2010
  • Synthesis of 4-Substituted Chiral PNA Monomers
    2010
  • Sequence-Specific Cleavage of DNA by Peptide Nucleic Acids Conjugated with Metal Complexes
    Toru Sugiyama; Keiko Ninomiya; Yasutada Imamura; Masaaki Kurihara; Masashi Takano and Atsushi Kittaka
    第46回ペプチド討論会, 04 Nov. 2009
  • 孔径,膜厚を制御したポーラスアノード酸化皮膜上でのヒト皮膚由来線維芽細胞の培養
    17 Sep. 2009
  • Culture conditions affecting cellular clump formation accompanying intercellular accumulation of type V collagen fibrils
    Kenji Uchida; Takanori Kihara; Yongchol Shin; Toshihiko Hayashi; Yasutada Imamura
    8th Pan Pacific Connective Tissue Societies Symposium, 06 Jun. 2009, Japanese Society for Connective Tissue Research, Japan Matrix Club
  • Intercellular accumulation of type V collagen fibrils in accordance with cell aggregation
    Takanori Kihara; Yasutada Imamura; Yukitoshi Takemura; Kazunori Mizuno; Eijiro Adachi; Toshihiko Hayashi
    8th Pan Pacific Connective Tissue Societies Symposium, 06 Jun. 2009, Japanese Society for Connective Tissue Research, Japan Matrix Club
  • Development of ELISA Measurement for Urinary 3-Hydroxyproline containing Peptides and its Preliminary Application to Community Healthy Persons and Cancer Patients
    Yasutada Imamura; Junichi Saito; Joji Itoh; Shigeo Matsuyama; Akie Maruta; Toshihiko Hayashi; Chu Sato; Norihito Wada; Kazuo Kashiwazaki; Yutaka Inagaki; Tetsu Watanabe; Yuko Kitagawa and Isao Okazaki
    8th Pan Pacific Connective Tissue Societies Symposium, 05 Jun. 2009, Japanese Society for Connective Tissue Research, Japan Matrix Club
  • Development of ELISA Measurement for Urinary 3-Hydroxyproline containing Peptides and its Preliminary Application to Community Healthy Persons and Cancer Patients
    2009
  • Culture conditions affecting cellular clump formation accompanying intercellular accumulation of type V collagen fibrils
    2009
  • Intercellular accumulation of type V collagen fibrils in accordance with cell aggregation
    2009
  • Sequence-Specific Cleavage of DNA by Peptide Nucleic Acids Conjugated with Metal Complexes
    2009
  • COOPERATIVE STRAND INVASION BY PEPTIDE NUCLEIC ACID
    @Toru Sugiyama; Yasutada Imamura; Masaaki Kurihara; Atsushi Kittaka
    第45回ペプチド討論会, 29 Oct. 2008
  • 協同的ストランドインベージョンによる二本鎖DNA内18塩基の厳密な認識
    26 Mar. 2008
  • COOPERATIVE STRAND INVASION BY PEPTIDE NUCLEIC ACID
    2008
  • A gradient motif of collagen fibril structure in the equine superficial digital flexor tendon
    Takafumi WATANABE; Yoshinao HOSAKA1; Hiromi UEDA; Kazushige TAKEHANA; @Yasutada IMAMURA
    7th Pan Pacific Connective Tissue Societies Symposium, 31 Oct. 2007
  • Cellular meshwork formation by human mesangial cells on type IV collagen gel
    @Yasutada Imamura.Takeshi Watanabe; Daisuke Kajimura; Toshihiko Hayashi
    7th Pan Pacific Connective Tissue Societies Symposium, 31 Oct. 2007
  • IV型コラーゲンゲル上でのヒトメサンギウム細胞による細胞メッシュワーク形成のタイムラプス観察
    09 May 2007
  • A gradient motif of collagen fibril structure in the equine superficial digital flexor tendon
    2007
  • Cellular meshwork formation by human mesangial cells on type IV collagen gel
    2007
  • Sequence-specific Recognition of Double-Stranded DNA by Cooperative Strand Invasion
    T. Sugiyama; Y. Imamura; W. Hakamata; M. Kurihara; A. Kittaka
    第33回核酸化学シンポジウム, 20 Nov. 2006
  • A new aspect of collagen biosynthesis:Switching and secretion of two conformational isomers of type IV collagen is controlled by proryl hydroxylation
    Daisuke Kajimura; Yukiko Ijima; Masayuki Kojima; Yuko Sekihara; Yasutada Imamura
    5th International Symposium on Advanced Technology, 08 Nov. 2006
  • 筋腱接合部のコラーゲン細線維の構造特性について
    22 Sep. 2006
  • Do non-triple helical basement membrane collagens exist along hepatic sinusoid?
    K.Yoshikawa; Y. Imamura et al.
    13th International Symposium on Cells of the Hepatic Sinusoid, 03 Sep. 2006
  • Production of non-triple helical type XVIII collagen
    @Kiwamu Yoshikawa; Yasutada Imamura et al.
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, 18 Jun. 2006
  • Gelatin form of type XVIII collagen
    11 May 2006
  • 3本鎖らせん構造をとらない基底膜コラーゲン
    Mar. 2006
  • Production of non-triple helical type XVIII collagen
    2006
  • Do non-triple helical basement membrane collagens exist along hepatic sinusoid?
    2006
  • A new aspect of collagen biosynthesis:Switching and secretion of two conformational isomers of type IV collagen is controlled by proryl hydroxylation
    2006
  • Sequence-specific Recognition of Double-Stranded DNA by Cooperative Strand Invasion
    2006
  • Accumulation and condensation of type V collagen fibrils in the intercellular space of cultured human fibroblasts
    @T.Kihara; Y.Takemura; K.Yoshikawa; K.Mizuno; E.Adachi; Y. Imamura; T.Hayashi
    6th Pan-pacific Connective Tissue Societies Symposium, 30 Nov. 2005
  • Atomic force microscopic observation of type V collagen molecules
    30 Nov. 2005
  • Does a gelatin form of type XVIII collagen exist ?
    Kiwamu Yoshikawa; @Yasutada Imamura; et al.
    6th Pan-pacific Connective Tissue Societies Symposium, 30 Nov. 2005
  • ウマ浅指屈筋腱のコラーゲン細線維直径を変化させる分子要因について
    29 Sep. 2005
  • XVIII型コラーゲン産生におよぼすアスコルビン酸の効果 -IV型コラーゲン生合成に対するアスコルビン酸の効果との相関
    26 May 2005
  • Accumulation and condensation of type V collagen fibrils in the intercellular space of cultured human fibroblasts
    2005
  • Atomic force microscopic observation of type V collagen molecules
    2005
  • Does a gelatin form of type XVIII collagen exist ?
    2005
  • Glycosylation in non-helical type IV collagen polypeptides : a possible stabilizing mechanism
    Y.Imamura et al.
    XIXth Meeting of the Federation of the European Connective Tissue Societies, 09 Jul. 2004
  • エーラス・ダンロス症候群 コラーゲン線維形成異常の観点から
    16 May 2004
  • Glycosylation in non-helical type IV collagen polypeptides : a possible stabilizing mechanism
    2004
  • Suppression of cell proliferation and migration of human fibrosarcoma cell, HT-1080, by type V collagen fibrils
    T. Shingai; Y. Imamura; T. Hayashi
    5th Pan-pacific Connective Tissue Societies Symposium, 03 Jun. 2003
  • Hydrogen peroxide activated pro-Matrix Metalloendopeptidases 2 and 9 degraded human native type IV collagen
    Y. Takeda; Y. Imamura; T. Hayashi
    5th Pan-pacific Connective Tissue Societies Symposium, 03 Jun. 2003
  • The effect of the intermittent exposure to ascorbate on the secretion form of type IV collagen
    H. Shibamoto; Y. Imamura; T. Hayashi
    5th Pan-pacific Connective Tissue Societies Symposium, 03 Jun. 2003
  • Reciprocal relation between triple-helical formation and O-glycosylation of type IV collagen polypeptides
    D. Kajimura; S. Takahashi; K. Yoshikawa; S. Hattori; Y. Imamura et al.
    The 11th International Symposium on Basement Membranes, 06 Mar. 2003
  • Hydrogen peroxide activates pro-Matrix Metalloendopeptidases 2 and 9
    Y. Takeda; Y. Imamura; T. Hayashi
    The 11th International Symposium on Basement Membranes, 06 Mar. 2003
  • Reciprocal relation between triple-helical formation and O-glycosylation of type IV collagen polypeptides
    2003
  • Hydrogen peroxide activates pro-Matrix Metalloendopeptidases 2 and 9
    2003
  • Suppression of cell proliferation and migration of human fibrosarcoma cell, HT-1080, by type V collagen fibrils
    2003
  • Hydrogen peroxide activated pro-Matrix Metalloendopeptidases 2 and 9 degraded human native type IV collagen
    2003
  • The effect of the intermittent exposure to ascorbate on the secretion form of type IV collagen
    2003
  • Ehlers-Danlos syndrome患者由来線維芽細胞の作る細胞層の解析:V型プロコラーゲンα1(V)鎖上のBMP-1切断部位欠失との相関
    14 Oct. 2002
  • O-glycosylation of non-helical α(IV) chains
    D. Kajimura; S. Takahashi; K. Yoshikawa; Y. Imamura; T. Hayashi
    The 10th International Symposium on Basement Membranes, 27 Sep. 2001
  • Detection of non-triple helical form of alpha chains of type IV collagen in cell layler and human placenta
    S. Takahashi; D. Kajimura; K. Yoshikawa; Y. Imamura; T. Hayashi
    The 10th International Symposium on Basement Membranes, 27 Sep. 2001
  • Type IV collagen aggregates for construction of endothelial like tissue structure
    T. Kihara; M. Hirose; Y. Imamura; T. Hayashi
    The 10th International Symposium on Basement Membranes, 27 Sep. 2001
  • Interactions of Vascular Endothelial Cells and Smooth Muscle related Cells With Type IV Collagen
    @T.Hayashi; Y.Imamura et al.
    International Conference on New Strategies for the Treatment of Liver Cirrhosis, 09 Jun. 2001
  • 尿3-Hydroxyprolineによるがん健診への応用 (フォーラム:特許につながる独創的結合組織研究)
    07 Jun. 2001
  • Interactions of Vascular Endothelial Cells and Smooth Muscle related Cells With Type IV Collagen
    T. Hayashi; Y. Imamura; K.Mizuno; K. Yoshikawa; M. Hirose; H. Yamano; T. Kihara; Y. Takeda; D. Kajimura; S.Takahashi
    International Conference on New Strategies for the Treatment of Liver Cirrhosis, 06 Jun. 2001
  • Interactions of Vascular Endothelial Cells and Smooth Muscle related Cells With Type IV Collagen
    2001
  • O-glycosylation of non-helical α(IV) chains
    2001
  • Detection of non-triple helical form of alpha chains of type IV collagen in cell layler and human placenta
    2001
  • Type IV collagen aggregates for construction of endothelial like tissue structure
    2001
  • Regulaation of Profiferation or Phenotypes of Smooth Muscle Cells Endothelial Cells by Type ⅣCollagen Aaggregates
    T. Hayashi; M. Hirose; T. Kihara; M. Yamato; K. Mizuno; Y. Imamura; Y. Takeda
    ECM2000: International Conference on the Biology & Pathology of the Extracellular Matrix, 13 Oct. 2000
  • Phenotype regulation of smooth muscle cells by reconstituted type IV collagen aggregattes
    @H. Yamano; K. Yoshikawa; Y. Takeda; K. Mizuno; Y. Imamura; M; Hirose; T. Hayashi
    International Symposium On Biomaterials And Drug Delivery Systems, 20 Aug. 2000
  • Facilitated proliferation of human vascular endothelial cells in culture by type IV collagen aggregates
    @T. Kihara; M. Hirose; M. Yamano; K. Mizuno; Y. Imamura; T. Hayashi :
    XVIIth Meeting of the Federation of the European Connective Tissue Societies, 01 Jul. 2000
  • The Pro-α3(IV) collagen chain: Complete Primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI collagen chains
    @Y. Imamura; I. C. Scott; D. S. Greenspan:
    XVIIth Meeting of the Federation of the European Connective Tissue Societies, 01 Jul. 2000
  • Stereochemical analysis of heparin-interaction sites of triple-helical collagen
    @K; Mizuno; Y. Imamura; T. Hayashi
    XVIIth Meeting of the Federation of the European Connective Tissue Societies, 01 Jul. 2000
  • Bone morphogenetic Protein-1 processes the NH2-terminal propeptide, and a Furin-like proprotein convertase processes the COOH terminal propeptide of Pro α1(V) collagen
    @Y. Imamura; B. M. Steiglitz; D. S. Greenspan
    First symposium of the international society for Matrix Biology, 14 Jun. 2000
  • ヘパリンとコラーゲンらせんの相互作用についての立体化学的考察
    23 May 2000
  • Cleavage of Procollagens by Bone Morphogenetic Protein-1 (BMP-1) (Symposium: Formation and processing of functional structure of extracellular matrix molecules)
    Y. Imamura; I. C. Scott; B. M. Steiglitz; and D. S. Greenspan
    第47回マトリックス研究会, 23 May 2000
  • Cleavage of Procollagens by Bone Morphogenetic Protein-1 (BMP-1) (Symposium: Formation and processing of functional structure of extracellular matrix molecules)
    2000
  • Bone morphogenetic Protein-1 processes the NH2-terminal propeptide, and a Furin-like proprotein convertase processes the COOH terminal propeptide of Pro α1(V) collagen
    2000
  • Facilitated proliferation of human vascular endothelial cells in culture by type IV collagen aggregates
    2000
  • The Pro-α3(IV) collagen chain: Complete Primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI collagen chains
    2000
  • Stereochemical analysis of heparin-interaction sites of triple-helical collagen
    2000
  • Phenotype regulation of smooth muscle cells by reconstituted type IV collagen aggregattes
    2000
  • Regulaation of Profiferation or Phenotypes of Smooth Muscle Cells Endothelial Cells by Type ⅣCollagen Aaggregates
    2000
  • Characterization of the type Ⅴ collagen triple-helcial domains in comparison with type I collagen and type Ⅱcollagen:Limitation in the lateral accretion of type Ⅴcollagen triple-helical domains
    @K. Mizuno; E. Adachi; O. Katsumata; Y. Imamura; T. Hayashi
    Gordon Research Conferences, 25 Jul. 1999
  • Type V collagen fibrils as new biomaterials in tissue engineering
    T. Kihara; Y. Takemura; Y. Imamura; K. Mizuno; And T. Hayashi
    International Symposium On Biomaterials And Drug Delivery Systems In Conjunction With 3rd Asian International Symposium On Polymeric Biomaterials Science, 14 Apr. 1999
  • Type V collagen fibrils as new biomaterials in tissue engineering
    1999
  • Characterization of the type Ⅴ collagen triple-helcial domains in comparison with type I collagen and type Ⅱcollagen:Limitation in the lateral accretion of type Ⅴcollagen triple-helical domains
    1999
  • 酢酸・尿素溶液によるヒト胎盤からのコラーゲンの抽出
    22 Sep. 1997
  • Structure and Function of Type IV Collagen and Type V Collagen,
    林利彦,中里浩一; 水野一乘; 安達栄治郎; 廣瀬志弘; 今村保忠
    Asian International Symposium on Polymeric Biomaterials Science, 14 May 1997
  • Structure and Function of Type IV Collagen and Type V Collagen
    @林利彦,中里浩一; 水野一乘; 安達栄治郎; 廣瀬志弘; 今村
    Asian International Symposium on Polymeric Biomaterials Science, 14 May 1997
  • Ⅳ型コラーゲンのプロセシング
    27 Mar. 1997
  • Ⅳ型コラーゲンα鎖分布からみた角膜上皮基底膜の特異性
    27 Mar. 1997
  • Structure and Function of Type IV Collagen and Type V Collagen,
    1997
  • Structure and Function of Type IV Collagen and Type V Collagen
    1997
  • Reassemblies of Isolated Type IV Collagen and Type V Collagen: Importance of triple-helical domains in the interactions
    林利彦; 水野一乘; 中里浩一; 安達栄治郎; 今村保忠; 村岡正敏; 岩田正夫; 佐々木翼; 武田康; 高橋誠一郎
    Internet World Congress on Biomedical Sciences, 09 Dec. 1996
  • Evidence for Extracellular Production of Short Type IV Collagen a-Chains in Human Fetal Lung Fibroblast Culture
    Y. Imamura; S. Takahashi; T. Sasaki; Y. Takeda; M. Iwata; M. Yamato; Y. Sado; and T. Hayashi
    3rd Pan-pacific Connective Tissue Societies Symposium, 30 Nov. 1996
  • 短鎖α1(Ⅳ)およびα2(Ⅳ)がウシレンズカプセル以外にヒト胎盤およびウシ腎臓に存在する
    26 Aug. 1996
  • ヒト胎児肺線維芽細胞によって産生されるコラーゲンタンパク質(NR180)とBAC(Basement membraneAssociated Collagen)との関係
    06 Jun. 1996
  • 眼組織におけるTypeXII collagenの局在
    06 Jun. 1996
  • 160Kα1(IV)は180Kα1(IV)(IV型コラーゲンα1)から由来する?
    31 Mar. 1996
  • ヒト皮膚線維芽細胞の長期間培養によって形成されるシート様構造体の主要構成タンパク質
    14 Mar. 1996
  • 正常組織由来Ⅳ型コラーゲンから再構成した網状構造と基底板の網状の微細形態,
    14 Mar. 1996
  • Evidence for Extracellular Production of Short Type IV Collagen a-Chains in Human Fetal Lung Fibroblast Culture
    1996
  • Reassemblies of Isolated Type IV Collagen and Type V Collagen: Importance of triple-helical domains in the interactions
    1996
  • ウシレンズカプセル組織中のIV型コラーゲンα1鎖には180kサイズと共に長さの異なる160kサイズのものがほぼ同量存在する
    15 Oct. 1995
  • 抗IV型コラーゲン抗体と反応する180Kポリペプチド鎖の特徴-α1(IV)鎖との相違
    15 Oct. 1995
  • 骨形成不全症患者由来皮膚線維芽細胞の培養によるシート状構造体の形成とそのタンパク質成分の分析
    22 Jun. 1995
  • 皮膚線維芽細胞が形成したシート構造体の主成分はI型コラーゲンおよびVI型コラーゲンである
    07 Sep. 1994
  • 線維芽細胞による基底膜コラーゲンの産生及び細胞層への沈着
    01 Oct. 1993
  • 骨形成不全症患者由来皮膚線維芽細胞の培養によって沈着したコラーゲン会合体の構造の特徴
    18 Mar. 1993
  • 筋小胞体Ca2+輸送ATPaseのCa輸送部位の解析:Gd3+イオンを用いた解析法の確立
    03 Nov. 1989
  • Gdイオンによる筋小胞体Ca2+輸送ATPaseのCa輸送部位の研究
    03 Oct. 1988
  • 筋小胞体Ca2+輸送ATPaseの輸送部位のMnイオンによる解析
    12 Oct. 1987
  • 筋小胞体Ca2+輸送ATPaseのトリプシン限定分解断片の精製と切断部位の同定
    20 Sep. 1986
  • 筋小胞体Ca2+輸送ATPaseの反応過程における構造変化
    06 Oct. 1984
  • トリプシン限定分解処理した筋小胞体Ca2+輸送ATPaseの活性
    06 Oct. 1984
  • トリプシン限定分解反応を用いた、筋小胞体Ca2+輸送ATPaseのリガンド、温度による高次構造変化の研究
    29 Sep. 1983
  • 筋小胞体Ca2+輸送ATPaseのトリプシン限定分解に対する温度及び各種リガンドの影響
    10 Oct. 1982

Works

  • 基底膜再構成に関する研究
    Sep. 2006 - Mar. 2007

Industrial Property Rights

  • 特願2004-372163, ヒト尿中3-ヒドロキシプロリンの免疫学的測定よび測定用キット
  • United States Patent : 6,759,528,B2, MAMMALIAN PRO-α3(V) COLLAGEN CHAIN GENES
    Daniel S. Greenspan; Yasutada Imamura

Research Themes

Member History

  • Apr. 2024 - Dec. 2025
    運営委員
  • Apr. 2024 - May 2025
    事務局理事
  • Apr. 2001 - Mar. 2015
    運営委員, Japan Matrix Club