Isolation and identification of angiogenesis inhibitors in rosehip and elucidation of their inhibitory mechanisms
Akira Takahashi; Rikuto Nakao; Yasutada Imamura; Yongchol Shin
26th Congress of the International Union Biochemistry and Molecular Biology, Sep. 2024, International Union Biochemistry and Molecular Biology
Notch signaling between endothelial cells and fibroblasts induces the expression of type IV collagen in new angiogenesis model using HUVEC’s spheroid
Kazuki Kukita; Yasutada Imamura; Yongchol Shin
26th Congress of the International Union Biochemistry and Molecular Biology., Sep. 2024, International Union Biochemistry and Molecular Biology
皮下Fasciaの弾性線維の可視化
16 Jun. 2024
血管新生において血管内皮細胞ー線維芽細胞間のNotchシグナルはIV型コラーゲンの発現を制御する
15 Jun. 2024
HUVECスフェロイドを⽤いた新規⾎管新⽣モデルにおける⾎管内⽪細胞-線維芽細胞間Notchシグナルを介したIV型コラーゲンの産⽣の制御
08 Dec. 2023
ローズヒップに含まれる血管新生阻害物質の分離・同定および阻害機構の解明
06 Dec. 2023
NTH a1(IV)によるVE-カドヘリンのエンドサイトーシス：Endo180の関与
25 Jun. 2023
浅層Fascia のコラーゲン線維構造
25 Jun. 2023
3本らせん構造を持たない IV 型コラーゲンポリペプチド鎖 (NTH α1(IV)) はVE- カドヘリンによる血管内皮細胞間の結合を抑制する
26 Jun. 2022
Fascia の線維構造の解析
25 Jun. 2022
The mechanism of production and secretion of non-triple helical type IV collagen during angiogenesis
Yongchol Shin; Yuta Kawanobe; Kazuki Kukita; Ryota Kawamura; Yasutada Imamura
2020 International Symposium on Novel and Sustainable Technology, 26 Nov. 2020, Southern Taiwan University of Science and Technology, [Invited]
トリfasciaの線維構造の解析
20 Sep. 2020
新規血管新生モデルによる基底膜形成メカニズムの解明
14 Sep. 2020
Inhibitory activity of sekothrixide on a drug efflux via P-glycoprotein
Ryoki Haruyama; Yongchol Shin; Yasutada Imamura
18th International Symposium on Advanced Technology, 13 Dec. 2019, The Southern Taiwan University of Science and Technology
Enhancement of the tumor cell migration on fibronectin by the metalloproteinase from Ovophis okinavensis snake venom
Yuna Saito; Yongchol Shin; Yasutada Imamura
18th International Symposium on Advanced Technology, 13 Dec. 2019, The Southern Taiwan University of Science and Technology
Involvement of NTH alpha 1 (IV) in formation of basement membrane-like structures around the endothelial network in a novel in vitro angiogenesis model
Yongchol Shin; Akane Moriya; Yuta Tohnishi; Takafumi Watanabe and Yasutada Imamura
18th International Symposium on Advanced Technology, 13 Dec. 2019, The Southern Taiwan University of Science and Technology
ヒメハブ粗毒由来Metalloproteinaseを用いたFibronectinを介する腫瘍細胞の遊走メカニズムの解明
06 Dec. 2019
Digestion of ADAMTS13 by Plasmin in Human Plasma Increase the Risk of Thrombotic Thrombocytopenic Purpura
Yongchol Shin; Haruki Miyake; Kenshi Togashi; Ryuichi Hiratsuka; Kana Endou-Ohnishi; Yasutada Imamura
The XXVII Congress of the International Society on Thrombosis and Hemostasis, 07 Jul. 2019, The International Society on Thrombosis and Hemostasis
Cleavage of von Willebrand Factor Multimers and Fibrinogen in Human Plasma by Plasmin: Effects on Hemostasis Response
Kenshi Togashi; Yongchol Shin; Sae Morita; Satoshi Suzuki; Yasutada Imamura
The XXVII Congress of the International Society on Thrombosis and Haemostasis, 07 Jul. 2019, The International Society on Thrombosis and Hemostasis
トリfascia の線維構造研究法の確立
31 May 2019
疑似低酸素条件での3 本らせん構造をもたないIV 型コラーゲンポリペプチド鎖,(NTHα1(IV)) の産生
31 May 2019
血管新生におけるアスコルビン酸の影響 3本らせん構造をとらないIV 型コラーゲンポリペプチド鎖(NTHα1( Ⅳ )) 産生
31 May 2019
Plasminによる血漿および血栓中のvon Willebrand factor multimersの切断：止血及び線溶への影響
30 Jun. 2018
ELISAを用いた尿中3-Hydroxyproline含有ペプチド測定法の開発と大腸癌マーカーとしての有用性の検討ELISAを用いた尿中3-Hydroxyproline含有ペプチド測定法の開発と大腸癌マーカーとしての有用性の検討
29 Jun. 2018
血管内皮細胞と線維芽細胞による共培養スフェロイドを用いた血管新生モデルにおける基底膜構築
07 Dec. 2017
Extracellular matrix in planarians
Kazuto Nakano,Yogchol Shin,and Yasutada Imamura
The 16th International Symposium on Advanced Technology, 02 Nov. 2017
Localization of extracellular matrix proteins on a new in vitro angiogenesis model using the co-culture spheroids with endothelial cells and fibroblasts
17 Jun. 2017
Production of non-triple helical structure type Ⅳ collagen polypeptide (NTHα1(Ⅳ))
17 Jun. 2017
Cell culture on type VI collagen aggregates derived from bovine cornea
17 Jun. 2017
血管内皮細胞と線維芽細胞による共培養スフェロイドを用いた新規血管新生モデル
30 Nov. 2016
ヒメハブ粗毒由来metalloproteinase MP09によるFibronectin切断部位の特定と細胞遊走の促進
30 Nov. 2016
Fibrin clotに取込まれたvon Willebrand factor multimersはPlaminによるfibrinの切断を促進する
27 Sep. 2016
血漿または fibrin clot での plasmin によるvon Willebrand factor multimer の切断
04 Sep. 2016
Fibronectinへの細胞接着を特異的に阻害するヒメハブ粗毒由来P-III metalloproteinase MP09 の機能解析と阻害メカニズムの解明
16 Jul. 2016
ウシ角膜由来Ⅵ型コラーゲン会合体を用いた細胞培養法
24 Jun. 2016
血漿中またはFibrin clot中でのPmによるVWFMの切断
18 Jun. 2016
血漿中のplasminによるADAMTS13の切断とそのVWF切断活性の低下
03 Dec. 2015
フィブロネクチンへの細胞接着を特異的に阻害するヒメハブ粗毒由来P-3 Metalloproteinase(MP09)の精製と阻害メカニズムの解明
03 Dec. 2015
ヒト血漿中でのplasminによる構造変化したVWFマルチマーの切断
01 Dec. 2015
Incorporation of a peptide nucleic acid into a normal human fibroblast cell reduced type I collagen production
Yasutada Imamura; Suzuka Tsuboi; Toru Sugiyama; Atsushi Kittaka; Yongchol Shin
10th Pan-Pacific Connective Tissue Societies Symposium, 25 Aug. 2015, Korean Society for Biochemistry and Molecular Biology
Isolation of a venom protein derived from the Ovophis okinavensis (Himehabu) which specifically inhibits cell adhesion to fibronectin and elucidation of the inhibition mechanism.
Hirotaka Yoshie; Yongchol Shin; Yuriko Okano; Toshihiro Takahashi; Takeshi Tohyama; Yasutada Imamura
10th Pan-Pacific Connective Tissue Societies Symposium, 25 Aug. 2015, Korean Society for Biochemistry and Molecular Biology
Plasminが及ぼすヒト血漿中のADAMTS13活性への影響
23 May 2015
フィブロネクチンへの細胞接着を特異的に阻害するヒメハブ粗毒由来タンパク質の精製と阻害メカニムの解明
15 May 2015
ナマココラーゲン線維間相互作用
15 May 2015
3本らせん構造をもたないIV型コラーゲンポリペプチド鎖の産生条件と細胞局在の検討
15 May 2015
Factors on the sea cucumber collagen fibrils which affect interactions between fibrils
Jun Igarashi; Syun Ito; Kazuya Noda; Yu Harada; Yongchol Shin; Kouji Murakami; Chihiro Mochizuki; Mitsunobu Sato; Yasutada Imamura
The 1st Innovation Forum of Advanced Engineering Education, 02 Nov. 2014, Kogakuin University and The Society of Pure and Applied Coordination Chemistry
Elucidation of the mechanism of ADAMTS13 cleavage by plasmin in blood plasma
Haruki Miyake; Yongchol Shin; Yoshinobu Umetsu; Ryuichi Hiratsuka; Akifumi Takahashi; Kana Endo; Kenji Soejima; Yasutada Imamura
The 1st Innovation Forum of Advanced Engineering Education, 02 Nov. 2014, Kogakuin University and The Society of Pure and Applied Coordination Chemistry
Isolation and characterization of venom protein derived from the Ovophis okinavensis (Himehabu) which specifically inhibit cell adhesion to fibronectin
Hirotaka Yoshie; Yongchol Shin; Toshihiro Takahashi; Misumi Masaki; Takeshi Tohyama; Yasutada Imamura
The 1st Innovation Forum of Advanced Engineering Education, 02 Nov. 2014, Kogakuin University and The Society of Pure and Applied Coordination Chemistry
血漿ADAMTS13のplasminによる切断の分子機構の解明
18 Oct. 2014
フィブロネクチンへの細胞接着を特異的に阻害するヒメハブ粗毒由来タンパク質の単離と解析
18 Oct. 2014
IV型コラーゲンの3本らせん形成に及ぼす細胞培養条件の影響
07 Jun. 2014
MC3T3-E1細胞によるアパタイト沈着はナマココラーゲン線維により促進される
07 Jun. 2014
血漿中でのplasminによるADAMTS13の切断にクリングルドメインが関与する
31 May 2014
細胞外基質への細胞接着を特異的に阻害するヒメハブ粗毒由来タンパク質の探索
03 Dec. 2013
Type I collagen produced by cells in ascorbate depletion shows a lower denaturation temperature
Takayuki Mineo; Yongchol Shin; Kaori Kitada; Suzuka Hara; Toshiki Uchida; Yasutada Imamura
9th Pan Pacific Connective Tissue Societies Symposium, Nov. 2013, Pan Pacific Connective Tissue Societies
Sea cucumber collagen fibrils as cell culture substrates
Yasutada Imamura; Takahisa Shinbo; Arisa Amano; Masashige Kodama; Yohsuke Iseki; Hiroaki Miyazaki; Yongchol Shin
9th Pan Pacific Connective Tissue Societies Symposium, Nov. 2013, Pan Pacific Connective Tissue Societies
ヒト血漿へのストレプトキナーゼ添加によって活性化したplasminは，ヒト血漿中ADAMTS13を切断する
01 Jun. 2013
溶血性連鎖球菌由来ストレプトキナーゼによって活性化したplasminはヒト血漿中ADAMTS13を切断する
16 Dec. 2012
Novel potential cause of Thrombotic thrombocytopenic purpura
Ryuichi Hiratsuka; Yongchol Shin; Kana Endo; Yasutada Imamura
The 11th International Symposium on Advanced Technology, 30 Oct. 2012, Kogakuin Univeristy
Development of blood vessel substitutes for chemical library screening
Yongchol Shin; Yu Matsushita; Yui Sakakibara; Takahisa Shinbo; Kazuaki Yanagawa; and Yasutada Imamura
The 11th International Symposium on Advanced Technology, 30 Oct. 2012, Kogakuin University
Capillary-Like Structure Formed by Vascular Endothelial Cells on Sea Cucumber Collagen Fibrils
T. Shinbo; Y. Shin; Y. Imamura
The 11th International Symposium on Advanced Technology, 30 Oct. 2012, Kogakuin University
ナマコ由来コラーゲン線維を用いた血管内皮細胞の管腔形成
07 Jun. 2012
Characterization of the snake venom protein from the crude venom of Naja atra (Taiwan cobra) that inhibits binding of the tumor cell to type IV collagen
○TOHYAMA; Takeshi;SHIN; Yongchol;SETO; Ryouko;SEKIGUCHI; Yasuyuki
26 Mar. 2012
IV型コラーゲンを取り入れた生体内環境を模した人工血管の可能性 -IV型コラーゲン会合体上で長期培養した血管内皮細胞の形態、機能の検討-
26 Mar. 2012
IV型コラーゲンを取り入れた生体内環境を模した人工血管の可能性
10 Mar. 2012
Characterization of the snake venom proteins from the crude venom of Naja atra (Taiwan cobra) that inhibit binding of the tumor cell to collagen
29 Mar. 2011
The artificial blood vessel that mimics in vivo environment using type IV collagen,Morphology and function of vascular endothelical cells cultured in long-term on the reconstituted aggregates of type IV collage
29 Mar. 2011
細胞とコラーゲンの接着を阻害する蛇毒由来タンパク質の探索
04 Dec. 2010
Ⅳ型コラーゲン会合体を用いた人工血管構築
04 Dec. 2010
ナマココラーゲン線維による細胞凝集体の形成
Aug. 2010
Culture conditions affecting cellular clump formation accompanying intercellular accumulation of type Vcollagen fibrils
Uchida K; Kihara T; Shin Y; Hayashi T; Imamura Y
8th Pan Pacific Connective Tissue Societies Symposium, 06 Jun. 2009
フォンビルブランド因子切断酵素ADAMTS13はN末端領域を欠失したplasminogenに特異的に結合する
22 Nov. 2008
ADAMTS13 interacts with Lys-plasminogen
Toshiyuki MIYATA; Yongchol SHIN; Koichi KOKAME; Masashi AKIYAMA; Kenji SOEJIMA
Gordon Research Conference, 29 Jun. 2008
血栓形成の分子機構：蛇毒蛋白質を用いた血小板凝集の機序の解明
28 Jun. 2008
ADAMTS13結合蛋白質の網羅的探索とその機能解析
22 Jan. 2008
ADAMTS13はLys-plasminogenに結合する
13 Dec. 2007
ADAMTS13結合蛋白質の網羅的探索
25 Aug. 2007
cDNA microarray
@Yongchol Shin; Ken W.Y. Cho
The 1st international workshop on Promotion of Xenopus functional genomics. JSPS Core-to-Core Program, 07 Jan. 2005, JSPS
Global analysis of activin/nodal targets
Tadayoshi Hayata; Souichi Ogata; Lauren M. Meek; Tetsuya Koide; Yongchol Shin; Daniel A. Peiffer; Arnold Liao; Atsushi Kitayama; Ken W.Y. Cho
10th International Xenopus Conference, Sep. 2004
Gene expression profiling during embryogenesis: Xenopus cDNA microarray
Dec. 2003
Identification of organizer genes using DNA microarrays
Ken W.Y. Cho; Tetsuya Koide; Yongchol Shin; Daniel A. Peiffer; Ira L. Blitz; Atsushi Kitayama; Makoto Mochii; Naoto Ueno
9th International Xenopus Conference, Aug. 2002
A cDNA microarray-based screen to identify direct target genes of activin/nodal signaling
Tadayoshi Hayata; Lauren M. Meek; Yongchol Shin; Souichi Ogata; Makoto Mochii; Atsushi Kitayama; Naoto Ueno; Ken W.Y. Cho
9th International Xenopus Conference, Aug. 2002
Synexpression groups in cDNA microarray
Danila Baldessari; Rainer Konig; Roland Eils; Nicolas Pollet; Ursula Fenger; Yongchol Shin; Ken W.Y. Cho; Naoto Ueno; Christof Niehrs
9th International Xenopus Conference, Aug. 2002
Use of a DNA microarray approach to identify novel neural genes in Xenopus
Yongchol Shin; Tetsuya Koide; Daniel A. Peiffer; Peter H. Tran; Makoto Mochii; Atsushi Kitayama; Naoto Ueno; Ken W.Y. Cho
Santa Cruz Conference on Developmental Biology, Aug. 2002
Identification of novel members of the activin signaling cascade by microarray analysis
Lauren M. Meek; Tadayoshi Hayata; Yongchol Shin; Naoto Ueno; Ken W.Y. Cho
Santa Cruz Conference on Developmental Biology, Aug. 2002
DNA microarray optimizations: increasing spot accuracy and automated identification of true microarray signals using Xenopus laevis as a model system
Daniel A. Peiffer; Yongchol Shin; Andreas von Bubnoff; Peter H. Tran; Makoto Mochii; Atsushi Kitayama; Naoto Ueno and Ken WY Cho
Society for Developmental Biology 61st Annual Meeting, 2002
DNA microarray analysis in Xenopus
Yongchol Shin; Lauren M. Meek; Peter H. Tran; Daniel A. Peiffer; Cherryl A. Nugas; Makoto Mochii; Atsushi Kitayama; Christof Niehrs; Naoto Ueno; Ken W.Y. Cho
14th International Congress of Developmental Biology, Jul. 2001
血小板結合タンパク質flavocetin-Aの血小板凝集阻害機構
Mar. 2000
コラーゲン惹起血小板阻害タンパク質rhodocetinの作用機序
Dec. 1999
Structural Analysis of Glycoprotein Ib Binding Protein, Flavocetin-A, Which Inhibits Platelet Aggregation
Yongchol Shin; Junko Hasegawa; Izumi Okuyama; Hiroshi Mizuno; Hideko Atoda and Takashi Morita
XVIIth Congress of the International Society on Thrombosis and Haemostasis, Aug. 1999, The International Society on Thrombosis and Haemostasis
Glycoprotein Ia/IIa Mediated Signal Transduction in Platelets
Katsue Inoue; Yukio Ozaki; Kaneo Satoh; Yi Wu; Yutaka Yatomi; Yongchol Shin; and Takashi Morita
XVIIth Congress of the International Society on Thrombosis and Haemostasis, Aug. 1999, The International Society on Thrombosis and Haemostasis
ヘビ毒由来のC型レクチン様タンパク質に見られる3D domain swapping –タンパク質分子多量化のメカニズム-
Jul. 1999
Glycoprotein Ia/IIa-mediated signal transduction in platelets
Jul. 1999
ハブ毒中に含まれているdisintegrinと出血因子は同一遺伝子産物である
Mar. 1999
血小板凝集を阻害するGPIb結合蛋白質flavocetin-Aのクローニング
Dec. 1998
血小板凝集を阻害するGPIb結合蛋白質flavocetin-Aの構造解析
Oct. 1998
Rhodocytin, a Functional Novel Platelet Agonist Belonging to the Heterodimeric C-type Lectin Family. Induces Platelet Aggregation Dependent Integrin α2β1
Yongchol Shin; Katsue Inoue; Kaneo Satoh; Yukio Ozaki; and Takashi Morita
5th Chinese-Japanese Symposium on Blood Coagulation, Fibrinolysis and Platelets, Oct. 1998
コラーゲン受容体GP Ia/IIa, GPVI の細胞内信号伝達系の差異
Sep. 1998
コラーゲン受容体GP Ia/IIa, GPVI の細胞内信号伝達系の差異
25 Mar. 1998
蛇毒由来Ｃ型レクチン様ドメインを有するヘテロダイマーの新たな機能
Sep. 1997
組織傷害によって誘発される膜結合型プロトロンビンアクチベーターの酵素化学的性質
Sep. 1997
蛇毒由来Ｃ型レクチン様ドメインを有するヘテロダイマーの新たな機能
05 Jul. 1997
Isolation and Characterization of a Functionally Novel Platelet Agonist from the Venom of Calloselasma rhodostoma
Yongchol Shin; Takashi Morita
XVIth Congress of the International Society on Thrombosis and Haemostasis, Jun. 1997, The International Society on Thrombosis and Haemostasis
F1-ATPaseの分子集合に関与するβサブユニット内のアミノ酸残基の解析
Sep. 1995
大腸菌ATP合成酵素におけるサブユニット間相互作用の解析；two hybrid系を用いた解析系の確立
Sep. 1995
大腸菌ATP合成酵素αサブユニットのカルボキシ末端に存在する活性調節部位の解析
Sep. 1995
大腸菌ATP合成酵素を構成するサブユニットの分子集合に必要なβサブユニット中のアミノ酸残基の解析
Sep. 1994
アミノ末端にGSTを融合したδまたはεサブユニットとα,β,γサブユニットによるF1-ATPaseの再構成
Sep. 1994
F1-ATPaseサブユニットの部分ペプチドおよびGST融合ペプチドを用いた分子集合の解析
Oct. 1993
大腸菌αβγ複合体再構成系とサブユニット部分ペプチドを用いた分子集合の解析
Oct. 1992
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